Lysergic acid diethylamide, commonly known as LSD (from German Lysergsäure-diethylamid), and known colloquially as acid or lucy is a potent psychedelic drug. Effects typically include intensified thoughts, emotions, and sensory perception.

DMT, or N,N-Dimethyltryptamine, is a potent naturally occurring psychedelic found in plants and trace amounts in the human brain. It's known for its brief but intense hallucinogenic effects, often associated with spiritual experiences, and its use carries legal and psychological risks, necessitating careful and supervised usage.

2C-B is a synthetic psychedelic drug of the 2C family, commonly used as a recreational drug. Initially synthesized by Alexander Shulgin in 1974, to date, the substance has limited scientific information regarding its pharmacological effects and pharmacokinetics on humans.

3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (tablet form), and molly or mandy (crystal form), is a potent empathogen–entactogen with stimulant and minor psychedelic properties primarily used for recreational purposes.

Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.

Cannabis, also known as marijuana among other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries.